Extragonadal Pelvic Yolk Sac Tumor in a Postpubertal Patient: Case Report With Radiologic Correlation and Review of the Literature

Yolk sac tumor, also referred to as endodermal sinus tumor, is an aggressive malignant germ cell neoplasm that most commonly originates in the gonad. Its occurrence in extra-gonadal sites is infrequent and is highly malignant, with only a handful of cases reported in the literature. With the help of this article, we want to make readers aware of the rare site of yolk sac tumor, its clinical presentation, and its radiological findings. As clinicians, we should be vigilant to consider differential diagnoses for an underlying etiology, like yolk sac tumor, for a patient presenting with a subcutaneous lump. Even though swelling in subcutaneous regions, in most cases, represents a benign diagnosis, malignant ones should always be kept in the back of the mind while managing patients. Variation in the site of extragonadal germ cell tumors has been highlighted with this paper, and herein, we aim to make readers aware of a rare and uncommon germ cell tumor, acknowledging the importance of imaging findings in making a diagnosis and the approach for its management.

Authors

Institutions

Publication Details

Journal
Clinical Case Reports
Published
2025-09-24
DOI
https://doi.org/10.1002/ccr3.70939
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Extragonadal Pelvic Yolk Sac Tumor in a Postpubertal Patient: Case Report With Radiologic Correlation and Review of the Literature

Saurav Jha, Elaine Phillips, Marjorie Safran, Saurabh Gupta
Clinical Case Reports
Testicular diseases and treatments
article

Extragonadal Pelvic Yolk Sac Tumor in a Postpubertal Patient: Case Report With Radiologic Correlation and Review of the Literature

Saurav Jha, Elaine Phillips, Marjorie Safran, Saurabh Gupta
article en

Abstract

Yolk sac tumor, also referred to as endodermal sinus tumor, is an aggressive malignant germ cell neoplasm that most commonly originates in the gonad. Its occurrence in extra-gonadal sites is infrequent and is highly malignant, with only a handful of cases reported in the literature. With the help of this article, we want to make readers aware of the rare site of yolk sac tumor, its clinical presentation, and its radiological findings. As clinicians, we should be vigilant to consider differential diagnoses for an underlying etiology, like yolk sac tumor, for a patient presenting with a subcutaneous lump. Even though swelling in subcutaneous regions, in most cases, represents a benign diagnosis, malignant ones should always be kept in the back of the mind while managing patients. Variation in the site of extragonadal germ cell tumors has been highlighted with this paper, and herein, we aim to make readers aware of a rare and uncommon germ cell tumor, acknowledging the importance of imaging findings in making a diagnosis and the approach for its management.

Clinical Case ReportsVol. 13(10)
Patan Academy of Health Sciences (NP), SUNY Upstate Medical University (US), Upstate University Hospital (US)
Openalex Percentile: Top 58%
Testicular diseases and treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.