A rare case of comprehensive diagnosis of diffuse large B-cell lymphoma of the ovary detected in the early postpartum period by ultrasound

Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous orphan lymphoproliferative disorder characterized by an aggressive course. Due to its unusual nature, primary ovarian lymphoma lacks specific clinical features and may be mistaken for other types of ovarian malignancies. It poses a dual diagnostic and therapeutic challenge. Imaging plays a central role in diagnosing ovarian lymphoma, and radiologists should be familiar with the sonographic, computed tomography (CT), and magnetic resonance imaging (MRI) features of this condition in order to guide diagnostic workup and avoid unnecessary adnexectomy. Particular attention should be paid to thorough evaluation of the adnexa during preconception screening and during routine obstetric ultrasound, which are typically performed at least three times throughout pregnancy: in early gestation and at 11–14 weeks and 19–21 weeks of pregnancy.

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Publication Details

Journal
Ultrasound & Functional Diagnostics
Published
2025-09-18
DOI
https://doi.org/10.24835/1607-0771-316
Primary Topic
Cancer Risks and Factors
Type
article
Field-Weighted Citation Impact
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article

A rare case of comprehensive diagnosis of diffuse large B-cell lymphoma of the ovary detected in the early postpartum period by ultrasound

N.I. Borisova, A.I. Ishchenko, А. М. Ковригина, Н. Б. Парамонова et al.
Ultrasound & Functional Diagnostics
Cancer Risks and Factors
article

A rare case of comprehensive diagnosis of diffuse large B-cell lymphoma of the ovary detected in the early postpartum period by ultrasound

N.I. Borisova, A.I. Ishchenko, А. М. Ковригина, Н. Б. Парамонова, Т. А. Демура, E. V. Minashkina, K. M. Shchepina, N. M. Khovanskaya
article en

Abstract

Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous orphan lymphoproliferative disorder characterized by an aggressive course. Due to its unusual nature, primary ovarian lymphoma lacks specific clinical features and may be mistaken for other types of ovarian malignancies. It poses a dual diagnostic and therapeutic challenge. Imaging plays a central role in diagnosing ovarian lymphoma, and radiologists should be familiar with the sonographic, computed tomography (CT), and magnetic resonance imaging (MRI) features of this condition in order to guide diagnostic workup and avoid unnecessary adnexectomy. Particular attention should be paid to thorough evaluation of the adnexa during preconception screening and during routine obstetric ultrasound, which are typically performed at least three times throughout pregnancy: in early gestation and at 11–14 weeks and 19–21 weeks of pregnancy.

Ultrasound & Functional DiagnosticsVol. 31(3)
Sechenov University (RU)
Openalex Percentile: Top 64%
Cancer Risks and Factors
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