Organotypic culture system for prepubertal mice testicular tissue: A comparative study
This study clarifies the differential effects of culture systems on the development of germ cells and Sertoli cells in ITTs, and provides a standardized organotypic platform for investigating spermatogenesis, male infertility, and potential therapeutic interventions.
Authors
- Hui Zhou (ORCID: https://orcid.org/0000-0003-0572-8976)
- Yu Cheng (ORCID: https://orcid.org/0000-0002-3816-3417)
- Xunwei Wu (ORCID: https://orcid.org/0000-0002-0822-1700)
- Xinyi Wang (ORCID: https://orcid.org/0009-0008-4477-6130)
- Liping Deng (ORCID: https://orcid.org/0000-0003-3981-6165)
- Honggang Li (ORCID: https://orcid.org/0000-0002-6666-8527)
Institutions
- Third Affiliated Hospital of Guangzhou Medical University (CN)
- Huazhong University of Science and Technology (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fendo.2025.1664628
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00