Effects of mRNA-VEGF@USPIO magnetic resonance probe on endothelial injury in cerebral aneurysm
The mRNA-VEGF@USPIO probe demonstrated significant efficacy in promoting endothelial repair and regeneration at the neck of cerebral aneurysms. This theranostic agent not only offers a novel treatment strategy for cerebral aneurysms, but its favorable MRI imaging performance also lays a foundation for further evaluating its potential diagnostic value.
Authors
- Haitao Lu (ORCID: https://orcid.org/0000-0002-1775-9780)
- Yanming Wang (ORCID: https://orcid.org/0000-0002-2886-2978)
- Jingyi Li (ORCID: https://orcid.org/0000-0002-3126-7889)
- Hong Zhao (ORCID: https://orcid.org/0000-0002-5253-6638)
- Jiang Zhao
- Yalan Chen (ORCID: https://orcid.org/0000-0003-1241-3892)
- Xiangyang Liu
Institutions
- Renji Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fneur.2025.1632617
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Pudong New Area Health Commission