Zanubrutinib as a salvage therapy for ibrutinib-resistant chronic lymphocytic leukemia: a case report

The findings from this case report suggest that zanubrutinib may provide a viable treatment option for patients with CLL/SLL who have progressed on ibrutinib. Further studies and clinical trials are warranted to confirm these observations and to explore the broader applicability of zanubrutinib in managing ibrutinib-resistant CLL/SLL.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-09-25
DOI
https://doi.org/10.3389/fonc.2025.1671124
Primary Topic
Chronic Lymphocytic Leukemia Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Zanubrutinib as a salvage therapy for ibrutinib-resistant chronic lymphocytic leukemia: a case report

Changhua Jing, Zhenhui Lv, Xueqiong Wu, Ping Lü et al.
Frontiers in Oncology
Chronic Lymphocytic Leukemia Research
article

Zanubrutinib as a salvage therapy for ibrutinib-resistant chronic lymphocytic leukemia: a case report

Changhua Jing, Zhenhui Lv, Xueqiong Wu, Ping Lü, X. Yi
article en

Abstract

The findings from this case report suggest that zanubrutinib may provide a viable treatment option for patients with CLL/SLL who have progressed on ibrutinib. Further studies and clinical trials are warranted to confirm these observations and to explore the broader applicability of zanubrutinib in managing ibrutinib-resistant CLL/SLL.

Frontiers in OncologyVol. 15
Central Hospital of Zibo (CN)
Openalex Percentile: Top 64%
Chronic Lymphocytic Leukemia Research
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