Causal relationship between gut microbiota and diabetic neuropathy: a Mendelian randomization and 16S rRNA sequencing analysis
This study integrates Mendelian randomization analysis with 16S rRNA fecal assessments from animal models and clinical patients, revealing that gut microbiota imbalances may contribute to diabetic neuropathy development and providing novel insights for its prevention and therapeutic strategies.
Authors
- Panwei Mu (ORCID: https://orcid.org/0000-0001-5413-6876)
- Dingbang Huang
- Ying Wang (ORCID: https://orcid.org/0000-0002-1819-294X)
- Yong Liang (ORCID: https://orcid.org/0000-0003-2212-6694)
- Youyou Lv
- Y. Linda Hu (ORCID: https://orcid.org/0009-0002-7263-3635)
- Dezhao Liu (ORCID: https://orcid.org/0000-0002-0422-5464)
Institutions
- Sun Yat-sen University (CN)
- Fifth Affiliated Hospital of Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fendo.2025.1632406
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81