Shared senescence-associated gene networks in PCOS and T2DM: biomarker identification and functional validation
This study revealed the potential connections between PCOS, T2DM, and aging-related molecular networks and signaling pathways and discovered multiple potential therapeutic targets. It provides new intervention directions for clinicians, especially based on aging mechanisms.
Authors
- Mingjian Kong (ORCID: https://orcid.org/0000-0003-1381-3468)
- Ziqi Dai (ORCID: https://orcid.org/0009-0002-0425-0149)
- Yihan Yang (ORCID: https://orcid.org/0000-0002-6377-050X)
- Kun Lou (ORCID: https://orcid.org/0000-0003-3701-9787)
- Dan Liu (ORCID: https://orcid.org/0000-0002-2198-3910)
- Xin Chen (ORCID: https://orcid.org/0000-0002-5310-5426)
- Tianjiao Li (ORCID: https://orcid.org/0000-0001-6934-1469)
- Xuesong Zhang (ORCID: https://orcid.org/0000-0003-2432-2090)
Institutions
- Changchun Obstetrics and Gynecology Hospital (CN)
- Changchun University of Chinese Medicine (CN)
- Changchun 208 Hospital (CN)
- The Affiliated Hospital to Changchun University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fendo.2025.1652178
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00