Acute Metabolic Complications of Diabetes in the Emergency Department of the CHNCAK of Touba: Epidemiological, Clinical, Therapeutic and Evolutionary Aspects

Introduction: Diabetes mellitus comprises a spectrum of metabolic disorders characterised by chronic hyperglycaemia arising from inadequate insulin secretion, impaired insulin action, or both; acute metabolic complications (AMCs) are abrupt metabolic derangements directly related to the natural history of diabetes. We sought to quantify the frequency of AMCs among emergency department admissions, describe their epidemiological and diagnostic profiles, and identify factors associated with their occurrence. Methods: Twelve-month retrospective descriptive analytic study at the Emergency Department of the National Hospital Center Cheikh Ahmadoul Khadim (Touba), including all adults (≥18 years) with known or newly diagnosed diabetes admitted for an AMC. Variables covered demographics, diabetes characteristics, presentation, precipitants, management, and short-term outcomes. Results: Among 141 eligible records, AMCs accounted for 1.8% of admissions. Mean age was 55 ± 15 years ; male-to-female ratio 1.27. Type 2 diabetes predominated (93.7%) ; duration <5 years in 53.1%. Fourteen percent were not on antidiabetic therapy; hypertension coexisted in 21.13%. The commonest presenting complaint was classic hyperglycaemic symptoms (polyuria–polydipsia) (28.4%). AMC types were isolated hyperglycaemia 62.4%, diabetic ketoacidosis 31.2%, and severe hypoglycaemia 6.4% ; in 21.27%, the AMC revealed previously undiagnosed diabetes. Principal precipitants were infection (34.75% ; with skin/soft-tissue sites in 48.9% of infections), drug-related causes (34%), and non-adherence (14%). Management yielded rapid stabilisation : 56% were observed for <24 hours, while 44% required admission (mean length of stay 2.1 ± 1.8 days). No in-hospital deaths occurred. Conclusions: In this referral emergency setting, AMCs represent a meaningful yet manageable burden and function as a barometer of diabetes care quality. Their frequency sometimes without an obvious trigger underscores gaps in screening, therapeutic education, and access to specialised care. These findings support strengthened prevention, standardised emergency department protocols, and system-level organisation of diabetes services.

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Publication Details

Journal
Saudi Journal of Medical and Pharmaceutical Sciences
Published
2025-09-18
DOI
https://doi.org/10.36348/sjmps.2025.v11i09.011
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
Type
article
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article

Acute Metabolic Complications of Diabetes in the Emergency Department of the CHNCAK of Touba: Epidemiological, Clinical, Therapeutic and Evolutionary Aspects

Boundia Djiba, Demba Diédhiou, Matar Ndiaye, Seydou Nourou Seck et al.
Saudi Journal of Medical and Pharmaceutical Sciences
Diabetes, Cardiovascular Risks, and Lipoproteins
article

Acute Metabolic Complications of Diabetes in the Emergency Department of the CHNCAK of Touba: Epidemiological, Clinical, Therapeutic and Evolutionary Aspects

Boundia Djiba, Demba Diédhiou, Matar Ndiaye, Seydou Nourou Seck, O. Diouf, Maïmouna Ndour Mbaye, Anna Sarr, Mouhamed Dieng, M. M. Niang, Michel Assane Ndour
article en

Abstract

Introduction: Diabetes mellitus comprises a spectrum of metabolic disorders characterised by chronic hyperglycaemia arising from inadequate insulin secretion, impaired insulin action, or both; acute metabolic complications (AMCs) are abrupt metabolic derangements directly related to the natural history of diabetes. We sought to quantify the frequency of AMCs among emergency department admissions, describe their epidemiological and diagnostic profiles, and identify factors associated with their occurrence. Methods: Twelve-month retrospective descriptive analytic study at the Emergency Department of the National Hospital Center Cheikh Ahmadoul Khadim (Touba), including all adults (≥18 years) with known or newly diagnosed diabetes admitted for an AMC. Variables covered demographics, diabetes characteristics, presentation, precipitants, management, and short-term outcomes. Results: Among 141 eligible records, AMCs accounted for 1.8% of admissions. Mean age was 55 ± 15 years ; male-to-female ratio 1.27. Type 2 diabetes predominated (93.7%) ; duration <5 years in 53.1%. Fourteen percent were not on antidiabetic therapy; hypertension coexisted in 21.13%. The commonest presenting complaint was classic hyperglycaemic symptoms (polyuria–polydipsia) (28.4%). AMC types were isolated hyperglycaemia 62.4%, diabetic ketoacidosis 31.2%, and severe hypoglycaemia 6.4% ; in 21.27%, the AMC revealed previously undiagnosed diabetes. Principal precipitants were infection (34.75% ; with skin/soft-tissue sites in 48.9% of infections), drug-related causes (34%), and non-adherence (14%). Management yielded rapid stabilisation : 56% were observed for <24 hours, while 44% required admission (mean length of stay 2.1 ± 1.8 days). No in-hospital deaths occurred. Conclusions: In this referral emergency setting, AMCs represent a meaningful yet manageable burden and function as a barometer of diabetes care quality. Their frequency sometimes without an obvious trigger underscores gaps in screening, therapeutic education, and access to specialised care. These findings support strengthened prevention, standardised emergency department protocols, and system-level organisation of diabetes services.

Saudi Journal of Medical and Pharmaceutical SciencesVol. 11(09)
Openalex Percentile: Top 65%
Diabetes, Cardiovascular Risks, and Lipoproteins
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