Mismatch Negativity and P300 in Children With Attention-Deficit/Hyperactivity Disorder (ADHD): A Comparative Event-Related Potential Study Using Healthy Siblings as Controls

These results indicate that children with ADHD demonstrate significant neurophysiological differences in MMN and P300 components compared to their healthy siblings. While ERPs show potential as objective and quantifiable markers of cognitive dysfunction in ADHD, their utility as standalone diagnostic indices remains limited, especially given this study's small sample size and absence of correlation with behavioral severity. Larger studies are needed to confirm and extend these findings before ERPs can be reliably used in clinical diagnostics for ADHD.