Exploring the relationships between clinical manifestations and sex hormones, thyroid hormones, and menstrual factors in female Parkinson’s disease patients

These findings suggest that the occurrence of motor complications in PWP may be correlated with prolactin, T3, and FT3 levels. Additionally, attention should be given to thyroid function and serum T3, T4, FT3, and FT4 levels in PWP, as lower levels may be associated with more severe motor symptoms, higher H-Y stages, and poorer cognitive function. Furthermore, older age at onset was inversely associated with motor complications in PWP, whereas a longer disease duration and higher NMSS score are risk factors.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-09-24
DOI
https://doi.org/10.3389/fmed.2025.1573768
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Exploring the relationships between clinical manifestations and sex hormones, thyroid hormones, and menstrual factors in female Parkinson’s disease patients

Jichen Du, Yi Zhong, Tao Feng, Jing Zhao et al.
Frontiers in Medicine
Parkinson's Disease Mechanisms and Treatments
article

Exploring the relationships between clinical manifestations and sex hormones, thyroid hormones, and menstrual factors in female Parkinson’s disease patients

Jichen Du, Yi Zhong, Tao Feng, Jing Zhao, Zhirong Wan, Peifu Wang, Fan Wang, Jilai Li
article en

Abstract

These findings suggest that the occurrence of motor complications in PWP may be correlated with prolactin, T3, and FT3 levels. Additionally, attention should be given to thyroid function and serum T3, T4, FT3, and FT4 levels in PWP, as lower levels may be associated with more severe motor symptoms, higher H-Y stages, and poorer cognitive function. Furthermore, older age at onset was inversely associated with motor complications in PWP, whereas a longer disease duration and higher NMSS score are risk factors.

Frontiers in MedicineVol. 12
Capital Medical University (CN), Beijing Geriatric Hospital (CN), Aerospace Center Hospital (CN)
Aerospace Center Hospital
Openalex Percentile: Top 62%
Parkinson's Disease Mechanisms and Treatments
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Exploring the relationships between clinical manifestations and sex hormones, thyroid hormones, and menstrual factors in female Parkinson’s disease patients — Jichen Du, Yi Zhong, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS