Pre-hospital proton pump inhibitor use and clinical outcomes in hospitalized COVID-19 patients: A retrospective case-control study
In this diverse, real-world United States cohort, chronic pre-hospital PPI use was independently associated with lower odds of intensive care unit admission, mechanical ventilation, and mortality among COVID-19 inpatients. These findings highlight a potentially protective role of PPIs and support continued therapy in eligible patients.
Authors
- Mithil Gowda Suresh (ORCID: https://orcid.org/0000-0002-1495-5444)
- Abinesh Sekar
- Sushmita Prabhu (ORCID: https://orcid.org/0000-0002-6186-8132)
- George M. Abraham (ORCID: https://orcid.org/0000-0003-4296-8362)
- Safia Mohamed (ORCID: https://orcid.org/0000-0002-0352-9810)
- Aalam Sohal (ORCID: https://orcid.org/0000-0001-8365-7240)
- Akash Batta (ORCID: https://orcid.org/0000-0002-7606-5826)
- Juniali Hatwal (ORCID: https://orcid.org/0000-0001-5433-0433)
- Harinivaas Shanmugavel Geetha (ORCID: https://orcid.org/0000-0001-6293-208X)
- Akshaya Sekar
Institutions
- Saint Vincent Hospital (US)
- Post Graduate Institute of Medical Education and Research (IN)
Publication Details
- Journal
- World Journal of Virology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.5501/wjv.v14.i3.109170
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00