Assessment of ventricular systolic rotation and deformation in premature ventricular contractions of different origins via three-dimensional speckle tracking imaging

3D-STI enables the quantitative assessment of PVC-related myocardial motion. (I) PVC beats exhibited the worst systolic function, while compensatory beats demonstrated enhanced compensatory function. (II) Left ventricular global longitudinal peak strain, basal radial peak strain, and strain time-to-peak difference may serve as sensitive indicators for early cardiac dysfunction. (III) Shortening of the coupling interval is a critical risk factor for cardiac functional deterioration. This study provides novel imaging-based evidence for the early identification of and clinical intervention in PVC-induced myocardial damage.