Statin therapy reduces vertebral artery atherosclerotic plaques: a case report with insight from vessel wall magnetic resonance imaging

This case provides significant imaging-based evidence of VA plaque regression following long-term statin therapy, as demonstrated via serial VW-MRI and angiographic studies. Despite prior assumptions regarding the limited responsiveness of vertebrobasilar circulation to statins, these findings demonstrate the potential utility of intensive lipid-lowering therapy in the management of posterior circulation atherosclerosis. VW-MRI may serve as a valuable tool for monitoring plaque evolution and therapeutic responses in cerebrovascular diseases.

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Publication Details

Journal
Quantitative Imaging in Medicine and Surgery
Published
2025-09-24
DOI
https://doi.org/10.21037/qims-2025-1156
Primary Topic
Cerebrovascular and Carotid Artery Diseases
Type
article
Field-Weighted Citation Impact
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article

Statin therapy reduces vertebral artery atherosclerotic plaques: a case report with insight from vessel wall magnetic resonance imaging

Byoung‐Soo Shin, Sang Yeon Kim, Hyun Goo Kang, Hyo Sung Kwak et al.
Quantitative Imaging in Medicine and Surgery
Cerebrovascular and Carotid Artery Diseases
article

Statin therapy reduces vertebral artery atherosclerotic plaques: a case report with insight from vessel wall magnetic resonance imaging

Byoung‐Soo Shin, Sang Yeon Kim, Hyun Goo Kang, Hyo Sung Kwak, Jimin Rhyu
article en

Abstract

This case provides significant imaging-based evidence of VA plaque regression following long-term statin therapy, as demonstrated via serial VW-MRI and angiographic studies. Despite prior assumptions regarding the limited responsiveness of vertebrobasilar circulation to statins, these findings demonstrate the potential utility of intensive lipid-lowering therapy in the management of posterior circulation atherosclerosis. VW-MRI may serve as a valuable tool for monitoring plaque evolution and therapeutic responses in cerebrovascular diseases.

Quantitative Imaging in Medicine and SurgeryVol. 15(10)
Jeonbuk National University Hospital (KR), Jeonbuk National University (KR)
Openalex Percentile: Top 63%
Cerebrovascular and Carotid Artery Diseases
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