Angiopoietin-1 induces survival and proliferation of hair follicle dermal papilla cells through integrin α5β1 signaling

Ang1 enhances HFDPC survival and proliferation through integrin α5β1-mediated signaling. In addition to its direct protective effects on DPCs, Ang1 may promote angiogenic support in the hair follicle microenvironment. These findings position Ang1 as a potential dual-action therapeutic candidate for androgenetic alopecia.