Regional high iron deposition is linked with cognitive impairments in peritoneal dialysis: a quantitative susceptibility mapping study
In peritoneal dialysis patients, abnormal cerebral iron deposition predominantly localizes to limbic-basal ganglia regions. Iron accumulation in the left amygdala may specifically mediate the development of multi-domain cognitive impairment. QSM represents a sensitive technique for early detection of pathological iron accumulation.
Authors
- Danhui Li (ORCID: https://orcid.org/0000-0003-3218-1961)
- Yonggui Wu (ORCID: https://orcid.org/0000-0001-6434-4759)
- Zhaohua Sun (ORCID: https://orcid.org/0000-0002-2410-3309)
- Yongjie Yin (ORCID: https://orcid.org/0000-0002-5261-7753)
- Jiuyu Yin
- Haibao Wang (ORCID: https://orcid.org/0000-0002-3174-1907)
- Yufan Zhou (ORCID: https://orcid.org/0000-0001-7188-3072)
- Xiangming Qi
- Shan Jiang (ORCID: https://orcid.org/0000-0003-1265-4776)
- Jie Fang (ORCID: https://orcid.org/0000-0002-1129-9576)
- Lei Yu (ORCID: https://orcid.org/0000-0002-0237-8758)
- Nan Feng
- Z. G. Chen
- Hongting Xu
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-09-24
- DOI
- https://doi.org/10.3389/fnagi.2025.1660734
- Primary Topic
- Dialysis and Renal Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00