REDD1 attenuates cholestatic liver fibrosis and suppresses PI3K/AKT/mTOR pathway
These findings highlight REDD1 as a potential therapeutic target for liver fibrosis, acting probably through modulation of the PI3K/AKT/mTOR pathway to mitigate fibrotic processes.
Authors
- Qizhi Shuai (ORCID: https://orcid.org/0000-0002-5284-0672)
- Junjie Ren (ORCID: https://orcid.org/0000-0001-7517-7888)
- Zixu Li
- Xin Liu (ORCID: https://orcid.org/0000-0003-3709-3709)
- Tingjuan Huang (ORCID: https://orcid.org/0000-0003-3879-3117)
- Xinrui Shi (ORCID: https://orcid.org/0009-0001-2188-3696)
- Yun Liu (ORCID: https://orcid.org/0000-0002-4697-261X)
- Xiaonan Li (ORCID: https://orcid.org/0009-0006-4107-9167)
Institutions
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-09-24
- DOI
- https://doi.org/10.3389/fmed.2025.1628260
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00