Pharmacovigilance study on old drugs repurposed for rare diseases across different indications: the case of fenfluramine
This study provided valuable evidence on the real-world safety of fenfluramine, suggesting that clinicians should place greater emphasis on monitoring its adverse effects during use. Medical staff should pay more attention to cardiac AEs on LGS patients and nervous system AEs on DS patients throughout the entire duration of fenfluramine treatment.
Authors
- Jinyu Xue (ORCID: https://orcid.org/0000-0002-8328-6424)
- Xin Yu (ORCID: https://orcid.org/0000-0002-0269-5649)
- Zhuomiao Lin
- Jiahong Zhong
Institutions
- Shantou University (CN)
- Meizhou City People's Hospital (CN)
- Second Affiliated Hospital of Shantou University Medical College (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.3389/fphar.2025.1682788
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province