Mechanistic study of Jiawei Zicao Plaster in atopic dermatitis via IL-17 signaling pathway and skin microbiome modulation
This study seeks to validate the efficacy of JPZ as a treatment for AD. Initial findings suggest that JPZ attains its therapeutic efficacy through the synergistic actions of IL-17 and antibacterial properties, providing a theoretical basis for the future development and application of this traditional Chinese medicine formula.
Authors
- Tingting Chen (ORCID: https://orcid.org/0000-0001-8278-7131)
- Di Chen (ORCID: https://orcid.org/0009-0004-1791-2302)
- Hongtao Zhang (ORCID: https://orcid.org/0000-0002-2904-0079)
- Bai Ling
- Yuru Yang
- Andong Wang (ORCID: https://orcid.org/0000-0003-2281-7946)
- Xiaotian Cheng
Institutions
- Zhejiang Chinese Medical University (CN)
- Xuzhou Medical College (CN)
- Nantong University (CN)
- Ningbo No. 2 Hospital (CN)
- Yancheng First People's Hospital (CN)
- Ningbo University Affiliated Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.3389/fmicb.2025.1668089
- Citations
- 1
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.00
Funders
- Jiangsu Commission of Health
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Zhejiang Chinese Medical University
- Natural Science Foundation of Ningbo