Deciphering the role of zingiber officinale phytochemicals for the treatment of prostate cancer: Interactions of phytochemicals with androgen receptor prostate cancer mutant H874Y ligand binding domain

The results of current in-siico and in-vitro studies are important for gaining an understanding of the mechanisms of how the Zingiber officinale phytochemicals bind to the H874Y mutated ligand binding domain, which is important for the development of targeted therapy against Prostate Cancer Mutant H874Y.

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Publication Details

Journal
Urologic Oncology Seminars and Original Investigations
Published
2025-09-24
DOI
https://doi.org/10.1016/j.urolonc.2025.08.009
Primary Topic
Ginger and Zingiberaceae research
Type
article
Field-Weighted Citation Impact
0.00
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article

Deciphering the role of zingiber officinale phytochemicals for the treatment of prostate cancer: Interactions of phytochemicals with androgen receptor prostate cancer mutant H874Y ligand binding domain

Shahzad Rasheed, Sireen Abdul Rahim Shilbayeh, Guiyuan Lei, Shuai Yan et al.
Urologic Oncology Seminars and Original Investigations
Ginger and Zingiberaceae research
article

Deciphering the role of zingiber officinale phytochemicals for the treatment of prostate cancer: Interactions of phytochemicals with androgen receptor prostate cancer mutant H874Y ligand binding domain

Shahzad Rasheed, Sireen Abdul Rahim Shilbayeh, Guiyuan Lei, Shuai Yan, Xu Gao, Shahanavaj Khan, Saeed Vohra, Salah-Ud-Din Khan
article en

Abstract

The results of current in-siico and in-vitro studies are important for gaining an understanding of the mechanisms of how the Zingiber officinale phytochemicals bind to the H874Y mutated ligand binding domain, which is important for the development of targeted therapy against Prostate Cancer Mutant H874Y.

Urologic Oncology Seminars and Original InvestigationsVol. 43(12)
Princess Nourah bint Abdulrahman University (SA), Imam Mohammad ibn Saud Islamic University (SA), Riyadh Elm University (SA), Yan'an University (CN), China XD Group (China) (CN), Shenyang 242 Hospital (CN), Indian Institute of Technology Kanpur (IN)
Openalex Percentile: Top 66%
Ginger and Zingiberaceae research
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Deciphering the role of zingiber officinale phytochemicals for the treatment of prostate cancer: Interactions of phytochemicals with androgen receptor prostate cancer mutant H874Y ligand binding domain — Shahzad Rasheed, Sireen Abdul Rahim Shilbayeh, et al. · Urologic Oncology Seminars and Original Investigations (2025) | TGRS Research Map | TGRS