Impact of nonalcoholic fatty liver disease on the functional cure of nucleos(t)ide analogues-treated chronic hepatitis B patients add-on pegylated interferon therapy: a retrospective study

NAFLD does not affect the achievement of functional cure with PEG-IFN therapy in NAs-treated chronic hepatitis B patients. However, CHB patients with NAFLD show a reduced likelihood of ALT normalization during treatment.

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Publication Details

Journal
PeerJ
Published
2025-09-24
DOI
https://doi.org/10.7717/peerj.19972
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Impact of nonalcoholic fatty liver disease on the functional cure of nucleos(t)ide analogues-treated chronic hepatitis B patients add-on pegylated interferon therapy: a retrospective study

Juan Fu, Xia Wang, Xiucheng Pan, Guangde Yang et al.
PeerJ
Liver Disease Diagnosis and Treatment
article

Impact of nonalcoholic fatty liver disease on the functional cure of nucleos(t)ide analogues-treated chronic hepatitis B patients add-on pegylated interferon therapy: a retrospective study

Juan Fu, Xia Wang, Xiucheng Pan, Guangde Yang, Li Li, Ling Li, Huili Li, Yiru Zhao
article en

Abstract

NAFLD does not affect the achievement of functional cure with PEG-IFN therapy in NAs-treated chronic hepatitis B patients. However, CHB patients with NAFLD show a reduced likelihood of ALT normalization during treatment.

PeerJVol. 13
Xuzhou Medical College (CN)
Xuzhou Medical University
Openalex Percentile: Top 65%
Liver Disease Diagnosis and Treatment
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Impact of nonalcoholic fatty liver disease on the functional cure of nucleos(t)ide analogues-treated chronic hepatitis B patients add-on pegylated interferon therapy: a retrospective study — Juan Fu, Xia Wang, et al. · PeerJ (2025) | TGRS Research Map | TGRS