The Use and Impact on Treatment Decision of the 21-Gene Recurrence Score Assay for Patients With HR+/HER2− Early Breast Cancer in Portugal: A Nationwide Retrospective Cohort Study
RSA has been increasingly adopted in Portugal and influenced ACT decisions. PR and Ki-67 can help refine patient selection for RSA, particularly in resource-limited settings. Clinical trial results significantly shaped treatment patterns.
Authors
- Tiago Dias Domingues (ORCID: https://orcid.org/0000-0002-4034-4276)
- Diogo Martins-Branco (ORCID: https://orcid.org/0000-0002-7214-4818)
- Renato Cunha (ORCID: https://orcid.org/0000-0002-2287-5487)
- Ana Ferreira (ORCID: https://orcid.org/0009-0006-4367-6651)
- Diana Pessoa
- Teresa Padrão (ORCID: https://orcid.org/0000-0002-4199-7252)
- Diogo Alpuim Costa (ORCID: https://orcid.org/0000-0002-1377-3032)
- José Luís Passos‐Coelho (ORCID: https://orcid.org/0000-0002-9458-8604)
- Débora Cardoso
- Mário Fontes e Sousa
- Sandra Bento
- Susana Palma de Sousa
- Joana Alves Luís
- Joana Simões (ORCID: https://orcid.org/0000-0002-3587-8214)
- I. Pina
Institutions
- University of Lisbon (PT)
- University of Trás-os-Montes and Alto Douro (PT)
- Lusíada University of Lisbon (PT)
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
- IPO Porto (PT)
- CUF Porto Hospital (PT)
- Centro Hospitalar Lisboa Norte (PT)
- Centro De Medicina Veterinária Anjos De Assis (PT)
- Centro Hospitalar de Lisboa Ocidental (PT)
- Hospital de Santo António (PT)
- Hospital da Luz (PT)
- Lusíada University of Porto (PT)
- Hospital do Desterro (PT)
Publication Details
- Journal
- Clinical Breast Cancer
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1016/j.clbc.2025.09.013
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00