Ex vivo assessment of blue laser-activated berberine-loaded nanoniosomes in enhancing photodynamic therapy against Streptococcus mutans biofilm on tooth enamel
Blue laser-activated nNios@Ber significantly inhibit S. mutans biofilm formation and virulence gene expression, offering an effective and targeted approach for caries management. This photoactivated nNios@Ber enhances the photodynamic activity, providing a promising adjunct or alternative to conventional antimicrobial agents such as CHX in oral healthcare.
Authors
- Maryam Pourhajibagher (ORCID: https://orcid.org/0000-0002-2772-8136)
- Bahman Rahimi Esboei (ORCID: https://orcid.org/0000-0003-2595-9907)
- Abbas Bahador (ORCID: https://orcid.org/0000-0001-5308-7208)
- Ehsan Moghaddam
- Mohammadreza Moeininejad
Institutions
- Shahrekord University (IR)
- Tehran University of Medical Sciences (IR)
- Mazandaran University of Medical Sciences (IR)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1016/j.pdpdt.2025.105229
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00