Research Communication: The Cumulated Spontaneous Portosystemic Shunts ( <scp>SPSS</scp> ) Area Decreases After <scp>TIPS</scp> and Impacts on Prognosis
We evaluated the dynamics of spontaneous portosystemic shunts (SPSS) after transjugular intrahepatic portosystemic shunt (TIPS). Ninety patients with covered TIPS placement and contrast-enhanced CT scans before and after TIPS were included. Total SPSS area and total shunt area (including TIPS) were assessed. Median SPSS area (67.2-15.7 mm<sup>2</sup>; p < 0.001) decreased after TIPS, while total shunt area remained unchanged (67.2-75.8 mm<sup>2</sup>; p = 0.170). Relative SPSS area decrease was an independent protective factor for mortality (asHR: 0.19; 95% CI: 0.04-0.88; p = 0.034). In conclusion, SPSS decrease after TIPS and relative SPSS area change is independently linked to survival, while total shunt area remains unaltered.
Authors
- Mattias Mandorfer (ORCID: https://orcid.org/0000-0003-2330-0017)
- Katharina Lampichler (ORCID: https://orcid.org/0000-0002-9719-4694)
- Lukas Reider
- Nina Dominik (ORCID: https://orcid.org/0009-0009-4615-915X)
- Paul Thöne (ORCID: https://orcid.org/0009-0001-1618-476X)
- Lukas Hartl (ORCID: https://orcid.org/0000-0003-3398-6120)
- Ulrika Asenbaum (ORCID: https://orcid.org/0000-0002-5850-7598)
- Susanne Riegler (ORCID: https://orcid.org/0009-0007-4529-9498)
- M Trauner
- Thomas Reiberger (ORCID: https://orcid.org/0000-0002-4590-3583)
- Theresa Bucsics (ORCID: https://orcid.org/0000-0003-3901-4111)
- Maria Schoder
- Georg Kramer (ORCID: https://orcid.org/0009-0008-1736-3699)
- Marlene Hintersteininger
- Christian Sebesta (ORCID: https://orcid.org/0009-0001-7504-8506)
Institutions
- Medical University of Vienna (AT)
Publication Details
- Journal
- Alimentary Pharmacology & Therapeutics
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1111/apt.70381
- Citations
- 1
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- Österreichische Nationalstiftung für Forschung, Technologie und Entwicklung
- Christian Doppler Forschungsgesellschaft
- Bundesministerium für Digitalisierung und Wirtschaftsstandort
- Ludwig Boltzmann Gesellschaft
- Österreichische Gesellschaft für Gastroenterologie und Hepatologie