First-in-human e-Flash radiotherapy using a modified conventional C-arm linear accelerator
We demonstrate first-in-human application of e-Flash delivered by a modified conventional linear accelerator. Conversion of conventional linacs into e-Flash systems will accelerate testing Flash radiotherapy in clinical trials.
Authors
- Riccardo Dal Bello (ORCID: https://orcid.org/0000-0002-8755-377X)
- Stephanie Tanadini‐Lang (ORCID: https://orcid.org/0000-0002-4387-1522)
- Debra Fesslmeier
- Egle Ramelyte (ORCID: https://orcid.org/0000-0001-8262-8608)
- Lena Tirpak
- Matthias Gückenberger (ORCID: https://orcid.org/0000-0002-7146-9071)
- Ricky A. Sharma (ORCID: https://orcid.org/0000-0002-4873-9918)
- J. Krayenbuehl
- Marta Vilalta
- Panagiotis Balermpas (ORCID: https://orcid.org/0000-0001-5261-6446)
- S. Psoroulas (ORCID: https://orcid.org/0000-0001-7576-3238)
- Jens von der Grün (ORCID: https://orcid.org/0000-0002-9371-7814)
- Joanna Mangana (ORCID: https://orcid.org/0000-0003-3962-7575)
- Wendy M. Smith (ORCID: https://orcid.org/0000-0001-9830-9601)
Institutions
- University of Zurich (CH)
- University Hospital of Zurich (CH)
- Varian Medical Systems (United States) (US)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1016/j.ctro.2025.101047
- Citations
- 1
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Varian Medical Systems