Quantifying the flash effect and its dependence on average dose rate in vivo for 6 MeV electron and 6 MV photon beams
This study shows that an increase in average dose rate delays the onset, and reduces the severity, of radiation induced skin toxicity in mice following hemi-thorax irradiation. The FLASH sparing effect's magnitude and dependence on dose rate appear similar following irradiations using 6 MV photon and 6 MeV electron beams.
Authors
- Nathalie Lövgren
- Salomé Paillas
- Iain D. C. Tullis (ORCID: https://orcid.org/0000-0001-5148-0161)
- Kristoffer Petersson (ORCID: https://orcid.org/0000-0003-0300-5790)
- Edward R J F Taylor
Institutions
- University of Oxford (GB)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1016/j.ctro.2025.101052
- Citations
- 1
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Cancer Research UK
- Medical Research Council