Preoperative Functional Connectivity Predicts Antiparkinson Drug Change after Deep Brain Stimulation
Patient-specific motor connectivity enhances DBS outcome prediction and could aid detection and monitoring of basal ganglia disorders. Future work will validate and extend our models for multi-parameter MR prediction of standardized outcomes, toward the development of decision support tools for DBS. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Doris D. Wang (ORCID: https://orcid.org/0000-0001-6112-3002)
- Ian O. Bledsoe (ORCID: https://orcid.org/0000-0001-8885-8148)
- Jill L. Ostrem (ORCID: https://orcid.org/0000-0001-7018-9521)
- Philip A. Starr (ORCID: https://orcid.org/0000-0003-2733-4003)
- John Kornak (ORCID: https://orcid.org/0000-0002-0089-0619)
- Skyler Deutsch (ORCID: https://orcid.org/0000-0003-2261-5885)
- David Mikhael (ORCID: https://orcid.org/0000-0002-6188-3906)
- Sarah Wang (ORCID: https://orcid.org/0000-0003-2564-1798)
- Melanie A. Morrison (ORCID: https://orcid.org/0000-0002-5993-0515)
- J. L. Mehta
Institutions
- University of California, San Francisco (US)
- Neurological Surgery (US)
- University of California, Berkeley (US)
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1002/mds.70063
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Boston Scientific Corporation
- University College London