Effects of commonly used antibiotics on children’s developing gut microbiomes and resistomes in peri-urban Lima, Peru
Common antibiotics like amoxicillin and azithromycin appear to be key drivers of the paediatric gut resistome. Resistome perturbations appeared to be stronger, or persist for longer, than gut microbiome effects in this middle-income country setting.
Authors
- Colin J. Worby (ORCID: https://orcid.org/0000-0002-9132-7249)
- Robert H. Gilman (ORCID: https://orcid.org/0000-0002-9037-0712)
- Amy J. Pickering (ORCID: https://orcid.org/0000-0001-6193-2221)
- Mónica J. Pajuelo (ORCID: https://orcid.org/0000-0003-3662-2250)
- Maya Nadimpalli (ORCID: https://orcid.org/0000-0002-6526-116X)
- Ashlee M. Earl (ORCID: https://orcid.org/0000-0001-7857-9145)
- Neha Sehgal (ORCID: https://orcid.org/0009-0000-0930-8560)
Institutions
- Broad Institute (US)
- Johns Hopkins University (US)
- Emory University (US)
- Universidad Peruana Cayetano Heredia (PE)
- Chan Zuckerberg Initiative (United States) (US)
- University of California, Berkeley (US)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1093/jac/dkaf358
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00