Explainable Deep Learning System for Custom Report Generation in Breast Cancer Histology

Abstract Breast cancer is the most lethal type of cancer among women, one of the causes can be due to the lack of professionals to evaluate the results of medical images in time (Sharafaddini et al. Multimed Tools Appl, 1–112 2024). This problem is even greater in developing countries. In recent years, diagnostic tools based on artificial intelligence techniques have been developed to improve diagnosis time and results. In this work, we present a system that analyzes histopathological images obtained from breast tissue biopsies to design a classification system that distinguishes between benign and malignant tissue. To demonstrate that the proposed work is robust, multiple alternatives and combinations are studied to obtain the best cases. Finally, we compare the proposed approach with previous works. Furthermore, the developed system integrates explainable artificial intelligence techniques to produce a report to the physician, including a heat map with the areas the system has determined to be essential for classification.

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Publication Details

Journal
Cognitive Computation
Published
2025-09-24
DOI
https://doi.org/10.1007/s12559-025-10510-5
Primary Topic
AI in cancer detection
Type
article
Field-Weighted Citation Impact
0.00

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article

Explainable Deep Learning System for Custom Report Generation in Breast Cancer Histology

Manuel Domínguez-Morales, Aurora Polo-Rodríguez, Javier Civit-Masot, Luis Muñoz-Saavedra et al.
Cognitive Computation
AI in cancer detection
article

Explainable Deep Learning System for Custom Report Generation in Breast Cancer Histology

Manuel Domínguez-Morales, Aurora Polo-Rodríguez, Javier Civit-Masot, Luis Muñoz-Saavedra, Miguel Ángel Anguita-Molina
article en

Abstract

Abstract Breast cancer is the most lethal type of cancer among women, one of the causes can be due to the lack of professionals to evaluate the results of medical images in time (Sharafaddini et al. Multimed Tools Appl, 1–112 2024). This problem is even greater in developing countries. In recent years, diagnostic tools based on artificial intelligence techniques have been developed to improve diagnosis time and results. In this work, we present a system that analyzes histopathological images obtained from breast tissue biopsies to design a classification system that distinguishes between benign and malignant tissue. To demonstrate that the proposed work is robust, multiple alternatives and combinations are studied to obtain the best cases. Finally, we compare the proposed approach with previous works. Furthermore, the developed system integrates explainable artificial intelligence techniques to produce a report to the physician, including a heat map with the areas the system has determined to be essential for classification.

Cognitive ComputationVol. 17(5)
Universidad de Granada (ES), European Telecommunications Standards Institute (FR), Universidad de Sevilla (ES)
Universidad de Sevilla
Openalex Percentile: Top 86%
AI in cancer detection
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Explainable Deep Learning System for Custom Report Generation in Breast Cancer Histology — Manuel Domínguez-Morales, Aurora Polo-Rodríguez, et al. · Cognitive Computation (2025) | TGRS Research Map | TGRS