Policy Adherence to Antithrombotic Therapy for Prophylactic Anticoagulation in Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with COVID-19

Overall, 40 (80%) patients were started on enoxaparin per our center's institutional guidelines. Our study demonstrated an empiric enoxaparin dose of 0.5 mg/kg (maximum initial dose 60 mg) every 12 hours resulted in zero venous thromboembolism events. In conjunction with a median dose of 3.1 mg/kg/d of aspirin, these doses resulted in one bleeding event.

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Publication Details

Journal
The Journal of Pediatrics Clinical Practice
Published
2025-09-24
DOI
https://doi.org/10.1016/j.jpedcp.2025.200179
Primary Topic
Kawasaki Disease and Coronary Complications
Type
article
Field-Weighted Citation Impact
0.00
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article

Policy Adherence to Antithrombotic Therapy for Prophylactic Anticoagulation in Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with COVID-19

Carlton K.K. Lee, David Procaccini, Anna Sick-Samuels, Amanda Clouser et al.
The Journal of Pediatrics Clinical Practice
Kawasaki Disease and Coronary Complications
article

Policy Adherence to Antithrombotic Therapy for Prophylactic Anticoagulation in Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with COVID-19

Carlton K.K. Lee, David Procaccini, Anna Sick-Samuels, Amanda Clouser, Courtney E. Lawrence
article en

Abstract

Overall, 40 (80%) patients were started on enoxaparin per our center's institutional guidelines. Our study demonstrated an empiric enoxaparin dose of 0.5 mg/kg (maximum initial dose 60 mg) every 12 hours resulted in zero venous thromboembolism events. In conjunction with a median dose of 3.1 mg/kg/d of aspirin, these doses resulted in one bleeding event.

The Journal of Pediatrics Clinical PracticeVol. 18
Hackensack University Medical Center (US), American Red Cross (US), Johns Hopkins University (US), Johns Hopkins Medicine (US), Johns Hopkins Children's Center (US)
Openalex Percentile: Top 58%
Kawasaki Disease and Coronary Complications
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