Effect of Lignin and other Biopolymers on Hyperlipidemia and Gut Microbiota

So far, dietary fibers such as lignin, cellulose, pectin, guar gum, and psyllium have been well-studied for their preventive and therapeutical potential using animal and human models, especially for their beneficial effects on chronic metabolic conditions like dyslipidemia and related disorders. Dyslipidemia is a dangerous metabolic disorder related to hypercholesterolemia, coronary artery disease, and coronary heart disease. Earlier research has demonstrated that these dietary fibers can lower high serum lipid levels through different mechanisms. One of the most important mechanisms is the modification of gut microbiota. Increasing the abundance of lactic acid bacteria (LAB), which can metabolize different dietary fibers like lignin, may potentially reduce the cholesterol level. This review aims to provide useful insights and comprehensive discussions about current knowledge related to the properties, and the effects of dietary fibers mainly lignin in controlling hyperlipidemia and their effects on gut microbiota. Google Scholar, Research Gate, and Scopus are the search engines exploited to collect data by using lignin, biopolymers, gut microbiota, and hyperlipidemia as search terms.

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Publication Details

Journal
Jordan Journal of Pharmaceutical Sciences
Published
2025-09-24
DOI
https://doi.org/10.35516/jjps.v18i3.2077
Primary Topic
Lignin and Wood Chemistry
Type
article
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article

Effect of Lignin and other Biopolymers on Hyperlipidemia and Gut Microbiota

Pavel A. Gurikov, Joana Gil-Chávez, Mohammad A. A. Al‐Najjar, Husam Abazid et al.
Jordan Journal of Pharmaceutical Sciences
Lignin and Wood Chemistry
article

Effect of Lignin and other Biopolymers on Hyperlipidemia and Gut Microbiota

Pavel A. Gurikov, Joana Gil-Chávez, Mohammad A. A. Al‐Najjar, Husam Abazid, Tamara Athamneh, Eman Hasan, Amira Abu-Omar
article en

Abstract

So far, dietary fibers such as lignin, cellulose, pectin, guar gum, and psyllium have been well-studied for their preventive and therapeutical potential using animal and human models, especially for their beneficial effects on chronic metabolic conditions like dyslipidemia and related disorders. Dyslipidemia is a dangerous metabolic disorder related to hypercholesterolemia, coronary artery disease, and coronary heart disease. Earlier research has demonstrated that these dietary fibers can lower high serum lipid levels through different mechanisms. One of the most important mechanisms is the modification of gut microbiota. Increasing the abundance of lactic acid bacteria (LAB), which can metabolize different dietary fibers like lignin, may potentially reduce the cholesterol level. This review aims to provide useful insights and comprehensive discussions about current knowledge related to the properties, and the effects of dietary fibers mainly lignin in controlling hyperlipidemia and their effects on gut microbiota. Google Scholar, Research Gate, and Scopus are the search engines exploited to collect data by using lignin, biopolymers, gut microbiota, and hyperlipidemia as search terms.

Jordan Journal of Pharmaceutical SciencesVol. 18(3)
University of Jordan (JO), Applied Science Private University (JO), Jordan University of Science and Technology (JO), Universität Hamburg (DE), Novel (Germany) (DE), Hamburg University of Technology (DE)
Openalex Percentile: Top 75%
Lignin and Wood Chemistry
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Effect of Lignin and other Biopolymers on Hyperlipidemia and Gut Microbiota — Pavel A. Gurikov, Joana Gil-Chávez, et al. · Jordan Journal of Pharmaceutical Sciences (2025) | TGRS Research Map | TGRS