Polybrominated diphenyl ether profiles in adipose tissues of breast cancer patients and their carcinogenic potential investigation based on network toxicology and molecular docking
This integrative network study uncovers a mechanistic framwork linking adipose-accumulated PBDE mixtures to breast cancer pathogenesis. These findings provide insights for preventive and therapeutic interventions against PBDE-associated breast cancer.
Authors
- Yiteng Huang
- Qihao Zhao (ORCID: https://orcid.org/0000-0002-2344-2771)
- Haoyi Chen (ORCID: https://orcid.org/0000-0002-2293-1629)
- Yingming Jin
- Xi Liu (ORCID: https://orcid.org/0000-0003-3592-381X)
- Peng Lin (ORCID: https://orcid.org/0000-0003-3760-5575)
- Qian Chen
Institutions
- Shantou University (CN)
- Cancer Hospital of Shantou University Medical College (CN)
- First Affiliated Hospital of Shantou University Medical College (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Chemistry
- Published
- 2025-09-24
- DOI
- https://doi.org/10.3389/fchem.2025.1630283
- Citations
- 1
- Primary Topic
- Toxic Organic Pollutants Impact
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- Li Ka Shing Foundation
- National Natural Science Foundation of China