Potential activities to reduce the extent of substandard and falsified antibiotics across Africa and associated antimicrobial resistance

Antimicrobial resistance (AMR) is a global public health threat exacerbated by inappropriate antibiotic use. This is particularly important in Africa. The availability of substandard and falsified antibiotics, particularly among African countries, contributes to this adding to the burden of AMR. Poor monitoring and regulatory controls among African countries increases the public health risks of these antibiotics. This is especially the case in the informal sector. Addressing Africa’s battle against substandard and falsified antibiotics requires an integrated approach building on current WHO, Interpol and Pan-African initiatives. Activities include harmonizing regulatory activities across Africa and increasing the monitoring of available antibiotics as well as fines and sanctions for offenders. In addition, reducing the current high levels of inappropriate antibiotic use makes the market for falsified and substandard antibiotics considerably less attractive.

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Publication Details

Journal
Frontiers in Tropical Diseases
Published
2025-09-24
DOI
https://doi.org/10.3389/fitd.2025.1634029
Citations
2
Primary Topic
Pharmaceutical Quality and Counterfeiting
Type
article
Field-Weighted Citation Impact
3.76
Controls
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article

Potential activities to reduce the extent of substandard and falsified antibiotics across Africa and associated antimicrobial resistance

Tiyani Milta Maluleke, Bene D. Anand Paramadhas, Chukwuemeka Michael Ubaka, Aubrey Chichonyi Kalungia et al.
2 citations
Frontiers in Tropical Diseases
Pharmaceutical Quality and Counterfeiting
3.76
article

Potential activities to reduce the extent of substandard and falsified antibiotics across Africa and associated antimicrobial resistance

Tiyani Milta Maluleke, Bene D. Anand Paramadhas, Chukwuemeka Michael Ubaka, Aubrey Chichonyi Kalungia, Ester Hango, Johanna C. Meyer, Biset Asrade Mekonnen, Santosh Kumar, Brian Godman, Mukhethwa Munzhedzi
article en
2 citations

Abstract

Antimicrobial resistance (AMR) is a global public health threat exacerbated by inappropriate antibiotic use. This is particularly important in Africa. The availability of substandard and falsified antibiotics, particularly among African countries, contributes to this adding to the burden of AMR. Poor monitoring and regulatory controls among African countries increases the public health risks of these antibiotics. This is especially the case in the informal sector. Addressing Africa’s battle against substandard and falsified antibiotics requires an integrated approach building on current WHO, Interpol and Pan-African initiatives. Activities include harmonizing regulatory activities across Africa and increasing the monitoring of available antibiotics as well as fines and sanctions for offenders. In addition, reducing the current high levels of inappropriate antibiotic use makes the market for falsified and substandard antibiotics considerably less attractive.

Frontiers in Tropical DiseasesVol. 6
University of Nigeria (NG), St George's, University of London (GB), University of Strathclyde (GB), University of Namibia (NA), Sefako Makgatho Health Sciences University (ZA), Satavahana University (IN), University of Zambia (ZM), Ministry of Health (BW), Bahir Dar University (ET)
Openalex Percentile: Top 6%
Pharmaceutical Quality and Counterfeiting
3.76
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