Folic acid supplementation ameliorates alcohol-induced hepatic steatosis by inhibiting SREBP-1c-mediated lipogenesis
Serum folate and 5-MTHF are protective factors against AFLD. Furthermore, folic acid can ameliorate hepatic steatosis by inhibiting SREBP-1c-mediated lipogenesis, highlighting its potential in AFLD prevention and therapy.
Authors
- Tongtong Lan (ORCID: https://orcid.org/0000-0001-8470-0263)
- Jun-lei Yin
- Chen Liang (ORCID: https://orcid.org/0000-0002-4510-2014)
- Hao Sun (ORCID: https://orcid.org/0000-0002-6588-5108)
- Huichao Zhao
Institutions
- Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-09-24
- DOI
- https://doi.org/10.3389/fnut.2025.1668430
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- National Natural Science Foundation of China