Clinical characteristics and risk factors associated with severe community-acquired pneumonia infected by <i>Chlamydia psittaci</i>

This study explores the clinical features of psittacosis pneumonia and identifies key factors that may predict the severity of the disease. By analyzing data from 24 patients diagnosed using metagenomic next-generation sequencing (mNGS), the research uncovers important differences between severe and non-severe cases. The study finds that patients with severe psittacosis pneumonia have elevated levels of white blood cells (WBCs), neutrophils, neutrophil-to-lymphocyte ratio (NLR), C-reactive protein (hs-CRP), and procalcitonin (PCT), as well as a higher detection rate of fungi. Notably, the NLR emerges as a strong predictor of severe disease, suggesting its potential as an early diagnostic tool. These findings provide valuable insights that can help healthcare providers identify high-risk patients more quickly, allowing for timely interventions and improved management of the disease. Ultimately, this research could lead to better outcomes by guiding treatment decisions and enhancing our understanding of psittacosis pneumonia.

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Publication Details

Journal
Microbiology Spectrum
Published
2025-09-24
DOI
https://doi.org/10.1128/spectrum.00477-25
Citations
2
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
2.37
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article

Clinical characteristics and risk factors associated with severe community-acquired pneumonia infected by Chlamydia psittaci

Mao Huang, Zhengxia Wang, Ningfei Ji, Mingshun Zhang et al.
2 citations
Microbiology Spectrum
Reproductive tract infections research
2.37
article

Clinical characteristics and risk factors associated with severe community-acquired pneumonia infected by Chlamydia psittaci

Mao Huang, Zhengxia Wang, Ningfei Ji, Mingshun Zhang, Tingting Xu, Qi Yuan, Zhenzhen Wu, Wenkui Sun, Jiayue Wang, Zhongqi Chen
article en
2 citations

Abstract

This study explores the clinical features of psittacosis pneumonia and identifies key factors that may predict the severity of the disease. By analyzing data from 24 patients diagnosed using metagenomic next-generation sequencing (mNGS), the research uncovers important differences between severe and non-severe cases. The study finds that patients with severe psittacosis pneumonia have elevated levels of white blood cells (WBCs), neutrophils, neutrophil-to-lymphocyte ratio (NLR), C-reactive protein (hs-CRP), and procalcitonin (PCT), as well as a higher detection rate of fungi. Notably, the NLR emerges as a strong predictor of severe disease, suggesting its potential as an early diagnostic tool. These findings provide valuable insights that can help healthcare providers identify high-risk patients more quickly, allowing for timely interventions and improved management of the disease. Ultimately, this research could lead to better outcomes by guiding treatment decisions and enhancing our understanding of psittacosis pneumonia.

Microbiology SpectrumVol. 13(11)
Jiangsu Province Hospital (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 10%
Reproductive tract infections research
2.37
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