The Comparative Characteristics of Bioactivity of Materials Based on a Mixture of Calcium Phosphates and Polysaccharides

Abstract—Composite materials based on a mixture of calcium phosphates and polysaccharides (sodium alginate, chitosan, and hyaluronic acid) have been synthesized. Their properties can be adjusted by varying the filler/matrix ratio and drying temperature. The composition and morphology of samples and their degradation in a tris-buffered saline solution and a model SBF solution have been studied. It was found that a calcium phosphate layer is formed on the surface of samples in the SBF solution, which indicates the bioactivity of the samples. At the same time, a gradual transition of calcium ions from the surface of the material into the solution was observed in the tris-buffer medium.