Botulinum Toxin A for Improving Cosmetic Outcomes in Facial Wound Healing
Botulinum toxin A demonstrates significant efficacy in improving facial wound cosmetic outcomes with an excellent safety profile. Evidence-based dosing of 5 to 15 U/cm provides the best benefit-risk ratio. On the basis of cost-effectiveness evaluation of included studies, the intervention demonstrates favorable benefit-risk ratios for wounds in high-visibility facial areas, with economic modeling suggesting better utility for longer wounds where scar prevention outweighs treatment costs.
Authors
- Thamer M. AlBilasi (ORCID: https://orcid.org/0009-0006-2574-6345)
- Ahmed Naif Alolaywi (ORCID: https://orcid.org/0000-0002-3795-0785)
- Reem Mansour Kublan Alkublan
- Alanoud S. Bin Suayb
- Ahmed Y. Azzam (ORCID: https://orcid.org/0000-0002-4256-0159)
- Norah A. Almudawi (ORCID: https://orcid.org/0009-0008-2168-1454)
- Philip Solomon (ORCID: https://orcid.org/0000-0001-8880-1205)
- Rawan Mahmoud Alanazi
Institutions
- Riyadh Armed Forces Hospital (SA)
- University of Toronto (CA)
- Jouf University (SA)
- Imam Mohammad ibn Saud Islamic University (SA)
- Prince Mohammed bin Abdulaziz Hospital (SA)
- King Abdulaziz Hospital (SA)
- Dar Al Uloom University (SA)
- Artificial Intelligence in Medicine (Canada) (CA)
Publication Details
- Journal
- Journal of Craniofacial Surgery
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1097/scs.0000000000011973
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00