Caffeine and Its Metabolites Are Associated with Overactive Bladder: Evidence from Multiple Statistical Analysis Models in NHANES
Our work demonstrates a strong inverse relationship between urine caffeine metabolites and the occurrence of OAB. Among these metabolites, 1,3-DMX and 1-MX have the most pronounced impact on the combined effect. These findings suggest that the way caffeine is metabolized in the body could play a crucial role in the development of OAB.
Authors
- Xianwei Guo (ORCID: https://orcid.org/0000-0001-7446-1713)
- Lu Fang
- Qingxin Yang
- Hongqiang Xie (ORCID: https://orcid.org/0000-0003-3203-7679)
- Junle Wu
- Chao Yang
Institutions
- Xuzhou Medical College (CN)
- Anhui Medical University (CN)
- Soochow University (CN)
- The First People's Hospital of Changzhou (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Urologia Internationalis
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1159/000548384
- Primary Topic
- Coffee research and impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00