Manipulating Blood Flow Using a Dielectrophoretic Simulation Technique

This study presents a non-invasive method to accelerate bone fracture healing by enhancing local blood flow using dielectrophoresis (DEP). External coil systems generate non-uniform electric fields to manipulate red blood cells (RBCs) toward the fracture site, promoting vascularization. We explain DEP theory, RBC dielectric properties, and COMSOL Multiphysics simulations used to optimize coil design and frequency selection. Results indicate that DEP can double RBC flow speed, potentially reducing healing time safely and effectively. Limitations include the need for experimental validation and precise coil placement.

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Publication Details

Published
2025-08-07
DOI
https://doi.org/10.1109/acdsa65407.2025.11166345
Citations
1
Primary Topic
Microfluidic and Bio-sensing Technologies
Type
article
Field-Weighted Citation Impact
0.67
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article

Manipulating Blood Flow Using a Dielectrophoretic Simulation Technique

Erman Kibritoglu, Heba Yüksel, Vahit Gunes, Recep Tayyip Temiz
1 citations
Microfluidic and Bio-sensing Technologies
0.67
article

Manipulating Blood Flow Using a Dielectrophoretic Simulation Technique

Erman Kibritoglu, Heba Yüksel, Vahit Gunes, Recep Tayyip Temiz
article en
1 citations

Abstract

This study presents a non-invasive method to accelerate bone fracture healing by enhancing local blood flow using dielectrophoresis (DEP). External coil systems generate non-uniform electric fields to manipulate red blood cells (RBCs) toward the fracture site, promoting vascularization. We explain DEP theory, RBC dielectric properties, and COMSOL Multiphysics simulations used to optimize coil design and frequency selection. Results indicate that DEP can double RBC flow speed, potentially reducing healing time safely and effectively. Limitations include the need for experimental validation and precise coil placement.

Boğaziçi University (TR)
Openalex Percentile: Top 26%
Microfluidic and Bio-sensing Technologies
0.67
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