Evaluation of the Safety of Cefazolin Monotherapy in Outpatient Parenteral Antimicrobial Therapy at a Large Academic Medical Center
In outpatient parenteral antimicrobial therapy, weekly lab monitoring is often standard practice, even for antimicrobials with low complication rates. We reviewed 420 patients treated with cefazolin: lab abnormalities associated with readmission or treatment changes occurred in 2% of patients. Reduced-frequency monitoring may be reasonable for patients treated with cefazolin outpatient.
Authors
- Nicolas Poux (ORCID: https://orcid.org/0000-0003-1084-4533)
- David W. Kubiak (ORCID: https://orcid.org/0000-0003-3133-0945)
- Catherine Franklin
- Brandon Dionne (ORCID: https://orcid.org/0000-0003-2851-8883)
- Helen Stevenson
- Jeffrey C Pearson (ORCID: https://orcid.org/0000-0002-5276-1050)
- Charles H. DeWan
- Brian T. Chan (ORCID: https://orcid.org/0000-0002-6971-3039)
- Mark J Estano
- Eric M Gillett (ORCID: https://orcid.org/0000-0001-9528-8526)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1093/ofid/ofaf592
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of General Medical Sciences