Correlation between the mutation rates for ampC derepression and species or ampC genotypes in Enterobacter cloacae complex
ECC was found to have high mutation rate-inducible AmpC production with no species or ampC genotype differences. This highlights an important clinical concern, i.e., the high risk of treatment failure with third-generation cephalosporins in individuals with inducible AmpC-containing ECC.
Authors
- Qiulan Huang (ORCID: https://orcid.org/0000-0001-6478-7410)
- Yanrong Wu
- Jingyong Sun
- Lianyan Xie
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Jiading District Central Hospital (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1186/s12866-025-04310-y
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China