Predictive Factors of Suboptimal Response to Topical 0.1% Cyclosporine A Cationic Emulsion in Pediatric Vernal Keratoconjunctivitis: A Real-World Retrospective Study
Baseline disease severity, particularly the score for clinical signs, is a reliable predictor of response to 0.1% CsA CE. In patients exceeding the identified thresholds, early therapeutic escalation may be warranted to improve disease control and prevent structural complications.
Authors
- Chiara Mapelli
- Silvia Osnaghi
- Gaia Leone (ORCID: https://orcid.org/0000-0002-6397-1993)
- Daniele Giovanni Ghiglioni (ORCID: https://orcid.org/0000-0002-7219-9173)
- Francesco Viola (ORCID: https://orcid.org/0000-0003-1208-913X)
- Carlo Agostoni (ORCID: https://orcid.org/0000-0002-5006-0832)
- Marco Nassisi (ORCID: https://orcid.org/0000-0002-9354-9005)
- Costanza Altavilla
Institutions
- University of Milan (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
Publication Details
- Journal
- Ophthalmology and Therapy
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1007/s40123-025-01244-6
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00