<scp>sFlt</scp> ‐1/ <scp>PlGF</scp> ratio thresholds for diagnosing pre‐eclampsia in pregnant women with high blood pressure
In pregnant women with high blood pressure presenting between 24 + 0 and 38 + 6 weeks' gestation, the validated sFlt-1/PlGF ratio cut-offs for predicting early-onset PE and late-onset PE diagnosis within 1 week after biomarker measurement were 74 and 95, respectively. Furthermore, sFlt-1/PlGF ratios ≥ 74 and ≥ 95 were associated with increased risks of adverse maternal and perinatal outcomes, suggesting clinical utility for these cut-offs for risk stratification in Chinese women with a singleton pregnancy and high blood pressure. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.
Authors
- Huishu Liu (ORCID: https://orcid.org/0000-0002-1197-5343)
- Jieru Peng (ORCID: https://orcid.org/0000-0002-2789-3019)
- Xiaodan Di
- Xingfei Pan (ORCID: https://orcid.org/0000-0003-4715-6865)
- Yunshan Chen (ORCID: https://orcid.org/0000-0001-5134-8670)
- Peng Li (ORCID: https://orcid.org/0000-0003-1626-3385)
- G. Zhang
Institutions
- Dongguan People’s Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Ultrasound in Obstetrics and Gynecology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1002/uog.70075
- Citations
- 1
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 2.06