Single-cell RNA-seq reveals gene expression heterogeneity in NSCLC and its link to the immune microenvironment
Our single-cell transcriptomic dissection of NSCLC highlights cellular heterogeneity as well as potential biomarkers associated with immune microenvironment. The findings provide a foundation for the rational development of biomarker-driven personalized treatment and therapy by extending the cell-type specificity of current designs of NSCLC therapeutics.
Authors
- Hua Zhang (ORCID: https://orcid.org/0000-0001-9635-2542)
- Juan Ren (ORCID: https://orcid.org/0000-0002-8360-8286)
- Haiyong Wu
Institutions
- Hebei North University (CN)
- Zhangjiakou Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1007/s12672-025-03494-z
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00