Screening for individuals with postpartum depression by an attenuated and delayed niacin skin flushing response: a case control study
This study identified the characteristics of impaired niacin response in women with PPD, and established a potential screening standard for PPD, which is highly objective and operable. The niacin-blunted subgroup of PPD may imply a common biological basis, which provokes new thoughts in elucidating the pathological mechanisms of postpartum depression.
Authors
- Zhendong Xu (ORCID: https://orcid.org/0000-0002-2696-3492)
- Yan Zhuang (ORCID: https://orcid.org/0000-0002-6816-3071)
- Juan Zhang (ORCID: https://orcid.org/0000-0002-1161-1072)
- Chunling Wan (ORCID: https://orcid.org/0000-0002-0372-0041)
- Lize Xiong (ORCID: https://orcid.org/0000-0002-9204-8129)
- Yan Gao (ORCID: https://orcid.org/0000-0001-6905-0143)
- Jie Jiang (ORCID: https://orcid.org/0000-0001-6619-1936)
- Jun Li (ORCID: https://orcid.org/0000-0001-9940-3421)
- Qian Wang (ORCID: https://orcid.org/0000-0002-4713-5557)
- Zhiqiang Liu (ORCID: https://orcid.org/0000-0002-3489-9101)
- Dandan Wang (ORCID: https://orcid.org/0000-0002-5869-096X)
- Fuyi Shen (ORCID: https://orcid.org/0000-0001-5258-0287)
- Xiaowen Hu
- Xuhan Yang
Institutions
- Tongji University (CN)
- Shanghai Jiao Tong University (CN)
- Shanghai Changning Maternity and Infant Health Hospital (CN)
- National Center for Women and Children’s Health, China CDC (CN)
- Ministry of Education (KR)
- Shanghai First People's Hospital (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- Shanghai First Maternity and Infant Hospital (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1186/s12884-025-08040-x
- Primary Topic
- Maternal Mental Health During Pregnancy and Postpartum
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation