Screening for Leishmania spp. infection in patients treated with biologic agents for immune-mediated inflammatory diseases: results of an Italian multicentric prospective study
This study showed a high prevalence of asymptomatic Leishmania infection in Italian patients with IMID under treatment with biologic agents, with a north-to-south gradient. Given the risk of disease reactivation, these patients may benefit from close monitoring. Further research is warranted to clarify the clinical implications of these findings.
Authors
- Francesca Perandin (ORCID: https://orcid.org/0000-0003-3933-3892)
- Eugenia Carrillo (ORCID: https://orcid.org/0000-0002-7869-7915)
- Simone Baiocchi
- Michele Spinicci (ORCID: https://orcid.org/0000-0002-5377-7118)
- Sara Morselli (ORCID: https://orcid.org/0000-0002-8400-0467)
- Chiara Piubelli (ORCID: https://orcid.org/0000-0002-5739-3795)
- Javier Moreno (ORCID: https://orcid.org/0000-0003-0087-4659)
- Francesca Nacci (ORCID: https://orcid.org/0000-0002-2558-9785)
- Cinzia Scambi
- Filippo Lagi (ORCID: https://orcid.org/0000-0003-0999-6070)
- Lorena Bernardo (ORCID: https://orcid.org/0000-0002-6899-4844)
- Anna Barbiero (ORCID: https://orcid.org/0009-0004-4152-9346)
- Lorenzo Zammarchi (ORCID: https://orcid.org/0000-0003-0892-8404)
- Stefania Varani (ORCID: https://orcid.org/0000-0003-0862-4937)
- Salvatore Scarso (ORCID: https://orcid.org/0000-0003-2956-8997)
- Margherita Ortalli (ORCID: https://orcid.org/0000-0001-5447-8817)
- Emma Balducelli (ORCID: https://orcid.org/0009-0009-3154-5701)
- A. Torres (ORCID: https://orcid.org/0000-0001-5178-1917)
- Alessandro Bartoloni
- Andrea Angheben
Institutions
- Instituto de Salud Carlos III (ES)
- Ospedale Sacro Cuore Don Calabria (IT)
- Centro de Investigación Biomédica en Red (ES)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Azienda USL di Bologna (IT)
- University of Florence (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Tropical Medicine and Health
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1186/s41182-025-00802-9
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero della Salute
- Instituto de Salud Carlos III