Diagnostic performance of the systemic immune-inflammation index (SII) and sarcopenia index (SI) in sarcopenia and their prognostic value for clinical outcomes in hospitalized older patients

The combination of SII with CC and SI with CC demonstrated advantageous diagnostic accuracy in diagnosing sarcopenia compared to SII and SI used independently. SII may serve as a serum indicator for predicting all-cause mortality in hospitalized older patients, though this requires further external validation. Additional well-designed prospective studies with larger sample sizes are needed to confirm our findings.