Unveiling the mechanisms of yanhusuo’s therapeutic effects in neuropathic pain through network pharmacology, single-cell RNA sequencing, and molecular docking
This work systematically maps Yanhusuo's multi-target, multi-pathway therapeutic landscape in NP, offering a strategic foundation for mechanistic research and drug discovery. The identified bioactive candidates represent promising candidates for NP therapeutics.
Authors
- Canqing Yu (ORCID: https://orcid.org/0000-0002-0019-0014)
- Shanlian Suo
- Tingting Liu (ORCID: https://orcid.org/0000-0002-5144-5179)
- Rui Liu (ORCID: https://orcid.org/0000-0002-7439-7966)
- Haitao Dong
- Kaihan Zhuang
Institutions
- Lanzhou University Second Hospital (CN)
- Southern Medical University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1186/s41065-025-00551-z
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Gansu Province