Diagnostic accuracy of T-SPOT.TB and TST in detecting active tuberculosis in patients with rheumatic immune diseases: a fully matched comparative study
In RD patients with suspected ATB symptoms, both T-SPOT.TB and TST offer valuable diagnostic assistance. T-SPOT.TB demonstrates superior diagnostic accuracy, particularly in terms of sensitivity. Higher spot counts on T-SPOT.TB or larger induration diameters on TST should raise clinical suspicion for the presence of concurrent ATB.
Authors
- Yuanchun Li (ORCID: https://orcid.org/0000-0001-7143-8884)
- H J Wang (ORCID: https://orcid.org/0000-0002-0513-1806)
- Lifan Zhang (ORCID: https://orcid.org/0000-0002-8166-9173)
- Xiaoqing Liu (ORCID: https://orcid.org/0009-0004-4457-0926)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1186/s12879-025-11331-5
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shandong University
- Harbin Medical University
- Qilu Hospital of Shandong University
- Inner Mongolia Medical University
- Central South University
- Zhengzhou University
- Zhejiang University
- Sichuan University
- Shanghai Jiao Tong University
- Chinese Academy of Medical Sciences
- Nanjing Medical University
- Fourth Military Medical University
- Peking Union Medical College Hospital
- Peking Union Medical College
- Renji Hospital
- Xiangya Hospital, Central South University
- West China Hospital, Sichuan University