Aqueous extract of Peristrophe bivalvis leaf alleviates oxidative stress in L-NAME-induced hypertensive rats
Conclusively, the results of this research indicate that APBL significantly mitigated the oxidative stress caused by hypertension in rats. This antioxidant effect is likely due to its capacity to lower levels of endothelin-1 and angiotensin II, both of which are recognized for their role in inducing oxidative stress by augmenting the formation of reactive oxygen species.
Authors
- Esther Oluwasola Aluko (ORCID: https://orcid.org/0000-0001-6930-5708)
- Wahab Adekunle Oyeyemi (ORCID: https://orcid.org/0000-0001-9620-1234)
- Adesoji Adedipe Fasanmade (ORCID: https://orcid.org/0000-0002-4853-623X)
Institutions
- University of Ibadan (NG)
- Osun State University (NG)
- University of Uyo (NG)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1186/s12906-025-05071-x
- Citations
- 2
- Primary Topic
- Medicinal plant effects and applications
- Type
- article
- Field-Weighted Citation Impact
- 4.76