Characterizing Long-Chain 3-Hydroxy-Acyl-CoA Dehydrogenase Deficiency (LCHADD) Chorioretinopathy Using OCT and OCTA
Combined OCT/OCTA imaging enables visualization and quantification of structural and microvascular alterations in the chorioretinal slabs at different stages of LCHADD. The pathology of LCHADD impacts the deeper retinal plexuses more than the inner layers. OCT and OCTA parameters may improve understanding of the pathological changes in LCHADD chorioretinopathy and aid in monitoring disease progression.
Authors
- Melanie B. Gillingham (ORCID: https://orcid.org/0000-0003-0897-8268)
- Dongseok Choi (ORCID: https://orcid.org/0000-0002-1552-4072)
- Xiaohui Hua
- Yali Jia (ORCID: https://orcid.org/0000-0002-2784-1905)
- Mark E. Pennesi (ORCID: https://orcid.org/0000-0002-4943-6599)
- Tristan T. Hormel (ORCID: https://orcid.org/0000-0002-7242-1934)
- Jie Wang
Institutions
- Oregon Health & Science University (US)
- Retina Foundation of the Southwest (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1167/iovs.66.12.57
- Citations
- 1
- Primary Topic
- Metabolism and Genetic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.32